recombinant non structural protein 1 ns1 protein (Native Antigen Inc)
Structured Review

Recombinant Non Structural Protein 1 Ns1 Protein, supplied by Native Antigen Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant non structural protein 1 ns1 protein/product/Native Antigen Inc
Average 86 stars, based on 1 article reviews
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1) Product Images from "An optimized purified inactivated Zika vaccine provides sustained immunogenicity and protection in cynomolgus macaques"
Article Title: An optimized purified inactivated Zika vaccine provides sustained immunogenicity and protection in cynomolgus macaques
Journal: NPJ Vaccines
doi: 10.1038/s41541-020-0167-8
Figure Legend Snippet: a ZIKV Env-specific IgG ELISA titers, b ZIKV-specific microneutralization (MN 50 ) titers, and c NS1-specific IgG ELISA titers following IM vaccination of six cynomolgus macaques with each dose: 100 AU, 200 AU, or 400 AU of ZPIV-SP or 200 AU of ZPIV on day 0 and day 28 (ANOVA * P -value < 0.05; *** P -value < 0.001). Dotted lines: limit of quantification. Arrows: vaccination on D0 and D28.
Techniques Used: Enzyme-linked Immunosorbent Assay
Figure Legend Snippet: a Env-specific memory B-cell ELISpot results, b NS1-specific memory B-cell ELISpot results at baseline, day 90 and day 164 following IM vaccination of cynomolgus macaques with 100, 200, or 400 AU of ZPIV-SP or 200 AU of ZPIV on day 0 and day 28. Bar = Geometric mean. (ANOVA *** P -value < 0.001). Dotted line = responder cutoff.
Techniques Used: Enzyme-linked Immunospot
Figure Legend Snippet: a ZIKV Env-specific IgG ELISA titers, b ZIKV-specific microneutralization (MN50) titers, and c NS1-specific IgG ELISA titers following IM vaccination of cynomolgus macaques with ZPIV-SP 100 AU on day 0, day 28, and a booster on day 176. ANOVA ** P -value < 0.01. Horizontal dotted lines = limit of quantification. Arrows = vaccination on D0, D28, and boost. Vertical dotted line = boosting dose (D176).
Techniques Used: Enzyme-linked Immunosorbent Assay
Figure Legend Snippet: a Env-specific IgG ELISA titers, b ZIKV-specific microneutralization (MN 50 ) titers, and c NS1-specific IgG ELISA titers following challenge of cynomolgus macaques ( n = 6/group) on day 176 by the SC route with 10 5 PFU of PRVABC59 wt-ZIKA strain. (ANOVA ** P -value < 0.01; *** P -value < 0.001). Dotted line = limit of quantification.
Techniques Used: Enzyme-linked Immunosorbent Assay
Figure Legend Snippet: a prM/Env-specific memory B-cell ELISpot responses, b NS1-specific memory B-cell ELISpot responses at baseline, day 35 and day 112 following ZIKV challenge in cynomolgus macaques with 10 5 PFU of PRVABC59 wt-ZIKA strain. Bar = Geometric mean. (ANOVA * P -value < 0.05; ** P -value < 0.01; *** P -value < 0.001). Dotted line = responder cutoff. p.c. = post-challenge.
Techniques Used: Enzyme-linked Immunospot